The distinctive characteristic of the Pearl Eye is that it has white dots on the upper eyes. Numerous variations are found in wild Amphiprion clarkii, probably due to some degree of reproductive isolation of certain populations throughout its wide geographical distribution. Variation exists with respect to any combination of three characters—body color, caudal fin color, and the number of stripes. Body color includes yellow, tan, and black. Caudal fins can be white or yellow. The number of stripes varies from 2 to 3, while stripes may sometimes be inconspicuous.
Like all clownfishes, Amphiprion clarkii is a sequential hermaphrodite. The largest individual present will exert dominance and become reproductively female. The next largest fish will become reproductively male. Anecdotal aquarium literature suggests that the female Amphiprion clarkii is sometimes unable to inhibit the male-to-female sex change of the male within a colony, leading to multiple female colonies.
Specimens have been weaned to take aquarium pellets and flakes. Freshly frozen invertebrates such as ocean plankton, Mysis shrimp, brine shrimp, and chopped squid will be readily accepted.